The ones I would stay away from unless through medical advice are low calorie food plans that teach the body it's in a world of scarcity, which means long term yo yoing weight and slow metabolism, teaching your body to store fat.
The best one, well as an exercise professional, the healthiest types of exercise are based on the natural design of the human body, which hasn't changed much through evolution.
So the best, it's got to be Paleo!
However, I'm a trainer who enjoys healthy food, but Paleo is quite strict.
My advice would be eat as much Paleo type foods as you can especially Vegetables, followed by Lean Protein.
If your goal is to be very lean, then you have to be strict.
If your goal is to lead a healthy lifestyle like the rest of us, then a Paleo "inspired' plan is the way forward. Try and eat Paleo foods in abundance, then the less healthy foods like diary products should be consumed in smaller amounts and so on.
What the balance of Paleo foods does (slightly higher Protein and Healthy Fat, slightly lower high energy Carbohydrate) is stabilise our blood sugar, the key to healthy weight loss!
Paleo people didn't live long? Well they were nearly wild, they had a few threats to contend with, child mortality was low, just because they had access to only whole food, doesn't mean it was always in abundance, that we in the western world enjoy!
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